One of the most profound changes in the life of an organism is what Antonio Giraldez calls “embryonic puberty”: the stage when an early embryo stops taking instructions from its mother on how to develop and activates its own genome to kick out those instructions instead. This critical stage, called the maternal-to-zygote transition, happens in all embryos, from sea anemones to humans. Yet how it is regulated in the embryo is not yet known.

The ruling Samajwadi Party seemed to hurtle towards a split just before assembly elections in Uttar Pradesh after Chief Minister Akhilesh Yadav defiantly released a list of candidates for seats already allotted by his father and party chief Mulayam Singh Yadav to others on Thursday night. His list of 235 candidates includes several party leaders who are close to Akhilesh and who did not make it to the party’s official list announced a day before by Mulayam Singh Yadav. The rebels said they have been asked by the chief minister to go back to their constituencies and prepare to contest the elections.